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ims: Treatment modalities in paAlmoplantar hyperhydrosis(PPH) are limited to iontophoresis and topical application of Aluminium chloride salts that the latter complicated by irritant dermatitis. We evaluated the efficacy of salvia officinalis (sage) 5 % lotion in treatment of PPH. Sage is a native plant in middle east that is cheap and available.
Patients and methods: This is a prospective, randomized and double-blind clinical trial.The patients with severe and symmetrical PPH treated by topical application of sage lotion on the one side and placebo on the other side of the body,three times per day.The patients were visited with two weeks intervals until six weeks.The overall treatment response was estimated subjectively by the patients.
Results:35 patients involved in this study.Both drug and placebo reduced the severity of PPH.The reduction with drug was significantly greater than with placebo.Mean of remediation percent in drug treated side,after 2,4 and 6 weeks were 29.7%,33.2% and 37%respectively versus in placebo treated side were 13.6%,14.5%and 14.8%(P<0.001).
Conclusion:The 5% salvia officinalis lotion is a safe drug in treatment of PPH with moderate efficacy
آدرس مطب : اصفهان ، خیابان فیض ، ابتدای خیابان ارباب
تلفن : 36627780 - 0313